Maternal high-fat diet during the periconception period alone or throughout gestation-lactation alters BAT and glucose tolerance – Irene Peral-Sanchez, University of Southampton, UK
Irene Peral Sanchez completed her Bachelor’s Degree in Biology at Autonoma University (Madrid, Spain), where she achieved with honours the final degree project based on the comparison of two techniques applied in assisted reproduction. After that, she completed an MSc in Genetics and Cell Biology at Complutense University (Madrid, Spain). Her Master´s final project was carried out in INIA (Gametogenesis, Molecular Embryology and Transgenesis Group of Dr Alfonso Gutierrez Adan) and it involved research on reproductive aging in mice and culminated in a publication based on germ-cell telomere dynamics in outbred mice. Recently she was awarded with Marie Skłodowska-Curie actions PhD fellowship and she joined the Dohart-Net Periconceptional Programming of Health Training Network (under grant agreement 812660) under the supervision of Dr. Judith Eckert, Dr Sandrine Willaime-Morawek, Dr Neil Smith and Prof. Thomas Fleming at University of Southampton (UK).
Her research focus is the assessment of mechanisms and consequences of maternal HFD diet on embryo phenotype and programming of postnatal health and disease. Irene is studying the consequences and associated mechanisms of mouse maternal high fat diet inducing adverse programming of the blastocyst and lasting effects on offspring health, especially on metabolism. She is also identifying biomarkers of adverse programming within the maternal uterine fluid and serum for early adverse phenotype identification.
The impact of paternal diet on fetal growth and placental renin-angiotensin system gene expression and placental histology – Afsaneh Khoshkerdar, University of Nottingham, UK
Afsaneh Khoshkerdar is a vet surgeon who received her qualification as a Doctor of Veterinary Medicine (DVM) – a first class degree at Tabriz University, Iran. She then pursued a Master of Medical Science in Assisted Reproduction Technology degree (2017-2018) with merit at Nottingham University, UK. After completing her Master’s in ART, she pursued her PhD in gynaecology and obstetrics at Nottingham University in (2019-2022). Currently she is working in Dr Watkins’s lab, investigating the impact of paternal diet on the maternal metabolic health during gestation.
Modulation of FSHR quaternary structure directs FSH-dependent signalling responses – Uche Agwuegbo, King’s College London, UK
Uche Agwuegbo is a final year PhD student currently studying at King’s College London within the department of Women and Children’s Health, under the supervision of Dr Kim Jonas. Uche’s research focuses on understanding the role of follicle stimulating hormone receptor in reproductive health and disease. Her research investigates deciphering the role of receptor homomerisation in mediating receptor signal activation and ovarian response. She has presented her work as a poster at many symposiums and national conferences and gave an oral presentation at last years’ Fertility conference in Edinburgh.
Adverse metabolic PCOS traits in a hyperandrogenic PCOS mouse model improved following neurokinin 3 receptor antagonist treatment – Irene Sucquart, University of New South Wales, Australia
Irene Sucquart is a first-year PhD candidate at the University of New South Wales in Australia and her PhD project focuses on neuroendocrine androgen actions in the origins of polycystic ovary syndrome. She graduated from the University of Edinburgh in 2014 with a BSc (Hons) in reproductive biology. She then completed an MSc in human clinical embryology and assisted conception at the University of Dundee in 2015. Irene then became a research assistant at the University of Dundee and was involved in several research projects that focused mainly on male infertility.
Adverse metabolic PCOS features observed in a hyperandrogenic PCOS mouse model are improved by mitochondrial uncoupler BAM15 – Dr Valentina Rodriguez Paris, University of New South Wales, Australia
Dr Valentina Rodriguez Paris is a reproductive biologist specializing in female reproduction. She conducts basic discovery research on potential new treatments for Polycystic Ovary Syndrome (PCOS). Dr Rodriguez Paris was awarded her PhD July 2020 from UNSW Sydney and is currently a Postdoctoral Research Fellow at the Ovarian and Oocyte Biology Research Unit at UNSW Sydney, Australia.