Macrophages in the uterus are functionally specialised and continually replenished from the circulation Elizabeth Mann, Research Fellow, University of Manchester, UK
Selective Progesterone Receptor Modulator (SPRM) impacts upon uterine natural killer (uNK) cells and local immune mediators in the endometrium of women with fibroids and heavy menstrual bleeding (HMB) – Hui Wei Leow, Academic Foundation Year Doctor, University of Edinburgh, UK
Hui Wei Leow (Amanda) is currently an Academic Foundation Programme junior doctor at NHS Lothian and an Honorary Clinical Fellow at the University of Edinburgh. She is passionate about improving women’s health using robust scientific research. Her research focuses on local uterine mechanisms involved in menstruation and understanding the pathophysiology behind abnormal uterine bleeding. She was the president of Edinburgh University Obstetrics and Gynaecology Society (2017-2019) and was awarded the Royal College of Obstetrician and Gynaecology Undergraduate Academic Prize twice in 2017 and 2020. She hopes to pursue a career in clinical academia within the field of Obstetrics and Gynaecology.
Progesterone, but not interferon tau, regulates S100 calcium binding proteins in the ovine uterus during the peri-implantation period – Dr Claire Stenhouse, Post-Doctoral Research Associate, Texas A&SM University, USA
Dr Claire Stenhouse is an Assistant Research Scientist in the Department of Animal Science at Texas A&M University. Her research utilises large animals to investigate molecular signaling between the conceptus (fetus and associated placental membranes) and the endometrium during pregnancy recognition, implantation, and placentation. She is particularly interested in the regulation of placental mineral transport and the mechanisms regulating intrauterine growth restriction, with a goal of generating new knowledge to improve pregnancy success in both women and livestock.
Extracellular vesicle-mediated embryo maternal communication – can only mothers respond when embryos talk? – Keerthie Dissanayake, Doctoral Student, University of Tartu, Estonia
Keerthie Dissanayake graduated with MBBS from the Faculty of Medicine, University of Peradeniya, Sri Lanka. After serving several years as a medical officer in the government health service, he joined the University of Peradeniya as a lecturer in Anatomy at the Faculty of Medicine. His Mphil thesis involved clinical and immunological characterization of Rheumatoid arthritis. Currently, he is a final year doctoral student at the Institute of Biomedicine and Translational Medicine, University of Tartu, Estonia, under Prof. Alireza Fazeli. He is investigating the preimplantation embryo-derived extracellular vesicles as embryo quality markers and their role as mediators of embryo material communication.
Exposure of Ishikawa cells to 17β-oestradiol in a microfluidics device reveals changes to transcripts involved in cell proliferation that may promote endometrial cancer – Dr Niamh Forde, Associate Professor, University of Leeds, UK
Insulin exposed endometrial epithelial cells in a microfluidics device alters transcripts involved in translation that may modify implantation capacity of the endometrium – Soo Young Baik, MRes Student, University of Leeds, UK