The Bob Edwards Lecture: The first cleavage division in human embryos – Professor Geraldine Hartshorne, University of Warwick and Centre for Reproductive Medicine, UHCW NHS Trust, UK
By the end of the lecture, the audience will know that:
• First mitosis is longer than subsequent mitoses.
• Problems at first cleavage are not female age-related.
• Different nuclear configurations in one or both cells at 2c stage are compatible with live birth.
• Eggs and embryos unsuitable for use in treatment can be informative in research with results similar to fresh eggs.
Following a BSc in Biochemistry and Pharmacology at Leeds, Professor Geraldine Hartshorne studied her PhD under Bob Edwards at Cambridge. She then remained at Bourn Hall for three years, as Research Fellow at Darwin College and Assistant Editor of Human Reproduction. She moved to establish micromanipulation and cryopreservation at the Oxford IVF unit, continuing research as McIlrath Research Fellow at St Hilda’s College. After three years, she moved to Warwick as one of the first posts heralding the formation of Warwick Medical School. Her research focuses on human fetal oogenesis and topics relevant to clinical embryology. She is Scientific Director of the Centre for Reproductive Medicine as Person Responsible for research, driving new developments and research clinics. She led clinical embryology recognition through Fellowship of the Royal College of Pathologists, and is external examiner for two MSc programmes. She has supervised multiple PhDs and MDs. She is a principal fellow of the Higher Education Academy, a partner to the Health and Care Professions Council, and Head of Clinical Faculty at Warwick Medical School. She has advised several organisations including Department of Health, EU and HFEA. She is an associate editor of three journals. She has 73 publications and H index of 26.