14:00-16.00   SRF Early career researchers symposium

16.20-17.35    SRF post doctoral prize session & SRF-SRB exchange lecture
Chair: Richard Lea, Reader in Reproductive Biology, Chair, Ethics Clinical Review Panel, School of Veterinary Medicine, University of Nottingham
16:20             Anti-Müllerian hormone differentially alters SMAD signalling in human granulosa cells from women with normal ovaries or polycystic ovary syndrome (PCOS)Nafi Dilaver, St George’s, University of London, UK
16:35              Investigation of the transcriptome in granulosa-lutein cells from PCOS patients implicates gene networks involved in cholesterol metabolism  Avi Lerner, Imperial College London, UK
16:50              Patterns in ovine oocyte metabolism during preantral follicle developmentPaul McKeegan, University of Leeds, UK
17.05              Imaging of lipids and lipid metabolism in mouse oocytes and early embryos  Josephine Bradley, Cardiff University, UK
17:20             SRF-SRB Exchange Lecture – Quynh-Nhu Nguyen, Monash Biomedicine Discovery Institute, Monash University, Australia

17.35-17.45          Comfort break

17.45-18.45         SRF / SSR New Investigator Lectures
Chair: Franchesca Houghton, Programme Chair, SRF and Associate Professor in Stem Cells & Developmental Biology, Deputy Director of Postgraduate Studies, University of Southampton, UK
SRF New Investigator Lecture Amanda Sferruzzi-Perri, Royal Society Dorothy Hodgkin Research Fellow and University Lecturer in Physiology, University of Cambridge, UK
SSR New Investigator Lecture  Aritro Sen, Assistant Professor, Reproductive and Developmental Sciences Program, Michigan State University, USA

19:00-23:00   ACE social: Pub quiz and Curry – EastZEast Restaurant

19:00-23:00   BFS social – EastZEast Restaurant

19:00-23.00   SRF social – Revolucion de Cuba

Male Fertility

09:30-09.40   Chair’s welcome: Valentine Akande, Programme Chair, BFS, UK

09:40-10.10    How to make environment safe to protect male reproductive health  Jorma Toppari, Professor and Chairman or Physiology, University of Turku, Finland 

10:10-10.40    Impact of environment and lifestyle on fertility of the present and future generations  Richard Sharpe, MRC Centre for Reproductive Health, The Queen’s Medical Research Institute, University of Edinburgh, UK 

10:40-11.10    Environmental influences on male infertility  Allan Pacey, Professor of Andrology, The University of Sheffield, UK

11:50 – 12:40   Bob Edwards Memorial Lecture: IVF 40 years on, Happy Birthday Louise Brown Stephen Hillier, Honorary Professorial Fellow, Emeritus Professor of Reproductive Endocrinology, University of Edinburgh, UK

12:40 – 12:50   Update on Fertility Network UK  Susan Seenan, Chief Executive, Fertility Network UK

14:00 – 15:30  Parallel Session A  4 sessions of short papers

16:15 – 17:45  Update session 1

Reproductive Science Update ACE BAS ABA: Lifestyle impacts 

  • Temporal, regional and environmental influences on sperm quality Rebecca Sumner, Postdoctoral Research Associate, University of Nottingham, UK
  • Alcohol and smoking on sperm function Tina Kold Jensen, Professor, Syddansk Universitet, Denmark 
  • You are your biochemistry: Metabolism as key player in human fertility João Ramalho-Santos, Associate Professor, University of Coimbra, Portugal   

BFS Update: Challenges in fertility practice

  • Challenges in fertility practice Managing patients with recurrent implantation failure Nick Macklon, Professor of Obstetrics and Gynaecology, University of Copenhagen, Denmark and Medical Director, London Women’s Clinic and The Bridge Centre, London, UK
  • Understanding the role of NK cells in reproduction and infertility Ashley Moffett, Professor of Reproductive Immunology, University of Cambridge, UK
  • HFEA update Sally Cheshire, Chair of Health Education North West (HENW), Human Fertilisation and Embryology Authority, USA

SRF Update: Stem cells

  •  Insights into cell fate decisions from conserved model systems Ramiro Albeiro, Associate Professor Epigenetics, University of Nottingham
  • Role of endometrial stem cells in recurrent miscarriage Jan Brosens, Professor of  Obstetrics & Gynaecology, University of Warwick, UK
  • Single cell epigenomics in stem cells and embryos – Wolf Reik Babraham Institute, Cambridge, UK (INVITED)

Nursing Update: Developments in fertility practice

  • Pushing the boundaries in older women and poor responders undergoing IVF Harish Bhandari, Consultant Gynaecologist & Sub-specialist Reproductive Medicine and Surgery – ‎Leeds Fertility, UK
  • Transfolk – what fertility services might usefully know  – James Barrett, Lead Clinician, Charing Cross Gender Identity Clinic, UK
  • Use of adjuvants in fertility practice Raj Mathur, Consultant Gynaecologist and Subspecialist in Reproductive Medicine and Surgery, Saint Mary’s Hospital, Manchester, UK

17.45-18.45    Welcome reception and attended poster session with an introduction to Fertility Fest

18.30-19.15    Ferring symposium

20.00-00.00   Social: Comedy Club NightThe Blundell Street Supper Club

Female Fertility

08.00-09.00   Registration, refreshments, exhibition and poster presentations

08.10-08.55    Merck symposium

08.20-08.50    SRF – Reproduction Journal prize session
Spatiotemporal dynamics of Oct4 protein localization during preimplantation development in mice – Atsushi Fukuda, Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA

09.00-09.05   Chairs welcome: Karen Schnauffer, Programme Chair, ACE, UK

09.05-09.35    Impact of stress on fertility outcomes Kavita Vedhara, Professor of Health Psychology, Faculty of Medicine & Health Sciences, University of Nottingham, UK

09.35-10.05    Impact of microbiomes on female infertility Daniel DiGiulio, Clinical Instructor, Medicine – Infectious Diseases, Stanford University, School of Medicine, USA

10.05-11.05   Obesity, oocyte quality and inheritance of mtDNA Rebecca Robker, Associate Professor, University of Adelaide, Australia

11.15-11.55   BFS Patrick Steptoe: Preconception Interventions for women with PCOS – Richard Legro, Professor of Obstetrics and Gynaecology and Public Health Sciences, Penn State University College of Medicine, USA

12.05-13.15  Society AGMs

14.15  Parallel sessions B – 5 sessions with short oral presentations

16.30-18.00   Update session

ACE Update: How to identify the best sperm

  • Hyaluronic acid binding sperm selection for ICSI (HABSelect): Study outcomes and conclusions David Miller, Reader in Molecular Andrology and HABSelect Chief Investigator, University of Leeds, UK  
  • SPERM: Spectroscopic Probes of Energy Regulation and Metabolism Steven Reynolds, Research Fellow,Magnetic Resonance Expert, The University of Sheffield, UK (INVITED)
  • Mathematics of how sperm swim Hermes Gadêlha, Lecturer, University of York, UK (INVITED)

BFS Update: Surgical aspects of reproductive medicine

  • Surgical aspects of Reproductive Medicine Endometriosis and infertility Ying Cheong, Professor of Reproductive Medicine within Medicine, University of Southampton, UK
  • Managing uterine problems in fertility – Fibroids, polyps, anomalies Yacoub Khalaf, Director of the Assisted Conception Unit and HFEA Person Responsible, Guy’s and St Thomas’ Private Healthcare, UK
  • Surgical sperm recovery: Indications and options Kevin McEleny, Consultant Urologist/Andrologist, Newcastle upon Tyne Hospitals NHS Foundation Trust, UK

SRF Update: Microbiomes

  • Endometrial microbiome and transcriptomics guiding personalise embryo transfer Carlos Simón, Professor of Obstetrics and Gynaecology, University of Valencia, Spain
  • Impact of caesarean section on the gut microbiome and health status of the developing infant – John Cryan, Department of Anatomy and Neuroscience, University of Cork, Ireland
  • Understanding the implications of the vaginal microbiome in poor pregnancy outcomes – Phillip Bennett, Institute of Reproductive and Developmental Biology (IRDB), Imperial College London, UK

Ultrasound Update: ISUOG ultrasound session

  • 3D/4D ultrasound Nick Raine-Fenning, Clinical Director, Nuture Fertility, UK
  • HyCosy v HSG Thierry Van den Bosch, University Hospitals KU Leuven, Leuven, Belgium
  • Early pregnancy problems Tom Bourne, Adjunct Professor in the Department of Surgery & Cancer within the Faculty of Medicine, Imperial College London, UK

18.10-18.50  Sponsor’s symposium

19.40  Social: Conference Dinner – ACC Hall 

Offspring

08.55-09.00   Chairs welcome: Franchesca Houghton, Programme Chair, SRF and Associate Professor in Stem Cells & Developmental Biology, Deputy Director of Postgraduate Studies, University of Southampton, UK

09.00-09.50   Anne McLaren Distinguished Scientist Lecture – One orchestra, three conductors: How to fine tune early follicle development Kate Hardy, Professor of Reproductive Biology, Imperial College, London, UK

09.50-10.20    Fertility in male ICSI children Willem Verpoest, Belgium

11.20-12.35     Parallel sessions C  – 5 parallel sessions with short oral presentations x 5

13.50     Update session 3

Clinical Update

  • Time-lapse; then, now and next Amy Barrie, Senior Clinical Embryologist, IVI Cheshire, Chester, UK
  • Re-evaluating PGS: Current thoughts and controversies Sesh Kamal Sunkara, Consultant Gynaecologist and Subspecialist in Reproductive Medicine and Surgery, King’s College London, UK
  • Mitochondrial donation in practice Alison Murdoch, Professor of Reproductive Medicine and Head of Department, Institute of Genetic Medicine, Newcastle University, UK

Scientific Update

  • Effect of prenatal exposures to environmental toxins on female reproduction Paul Fowler, Chair in Translational Medical Sciences, University of Aberdeen, UK
  • Dads, diet and disease: the paternal programming of offspring health Adam Watkins, Assistant Professor of Reproductive Biology, University of Nottingham
  • Developmental and transmittable origins of obesity-associated health disorders Kelle Moley Washington University School of Medicine

15.05-15.35    Title TBC Thomas Hildebrandt, Leibniz Institute for Zoo and Wildlife Research, Berlin

15.35-15.55    Prize Giving

16.00-16.05   Closing remarks Jason Kasraie, Chair, ACE, UK

Close of conference